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Unlike some other vitamins, cobalamin is not synthesized in the body

That date assumes the vial stayed sealed and stayed within its labeled storage range

Many common medications like acid blockers and NSAIDs further deplete your ability to absorb it

[1] If you experience persistent or concerning symptoms after starting B12 supplements, particularly skin changes or gastrointestinal issues, it is advisable to discuss these with your GP rather than assuming they are directly caused by vitamin excess